San Francisco 49ers at Arizona Cardinals 11/21/2022 -NFL Betting Picks & Odds
San Francisco 49ers vs. Arizona Cardinals
NFL: 8:15pm
Nov. 21, 2022
TV: ESPN
Latest Odds : SF -8 ; OU 43.5
This Monday Night November 21st 2022 8pm the NFL football is back in action. The San Francisco 49ers are in Mexico City to face the Arizona Cardinals in Estadio Azteca. Stay tuned we've got you covered on all the best betting angles here at Picks and Parlays your leader in free sports betting picks!
The San Francisco 49ers are 5-4, on the road, sitting in 2nd place in the NFC west conference. Offensively the 49ers are averaging 247 passing yards, 123 rushing yards, and 22 points. Defensively the 49ers allow 218 passing yards, 82 rushing yards, and 18 points.
Key players for the 49ers are Quarterback Jimmy Garopalo completing 159 of 238 passes for 1931 yards, 11 touchdowns and 4 interceptions. Runningback with carries for yards and touchdowns and Receiver Brandon Aiyuk with 44 receptions for 567 yards and 4 touchdowns.
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The Cardunals are 4-6, on at home, sitting in 3rd place in the NFC West conference. Offensively the Cardinals are averaging 241 passing yards, 113 rushing yards, and 23 points. Defensively the Cardinals allow 262 passing yards, 110 rushing yards, and 25.8 points.
Key players for the Cardinals are Quarterback Kyler Murray completing 240 of 360 passes for 2168 yards 12 touchdowns 6 interceptions and 59.carries for 359 yards and 2 touchdowns and Receiver Marquise Brown with 43 receptions for 485 yards and 3 touchdowns.
Recent Betting Trends:
The 49ers are 5-4 SU in their last 10 games.
The under is 6-3 in the 49ers last 10 games.
The Cardinals are 4-6 SU in their last 10 games.
The over is 5-4-1 in the Cardinals last 10 games.
Free Betting Pick: Under 43.5
We think this will be a grinded out defensive battle. The under is the trend to follow in stand alone primetime NFL games. The under is 6-4 in the Cardinals and 49ers last 10 head to head games. Our best bet is the Under 43. Final score prediction the San Francisco 49ers win pushes the spread 24-16.